MESOTHERAPY treatments AT

PRP Mesotherapy

PRP Mesotherapy utilizes whole autologous blood, which undergoes high-speed centrifugation to separate red blood cells from the plasma. This plasma is then centrifuged again and activated via a specialized kit to obtain a small amount of plasma with a concentration of platelets and growth factors 3 to 9 times higher than that of normal blood.

PRP stimulates fibroblast proliferation and promotes the synthesis of the skin matrix, particularly collagen, helping to fill pitted scars and improve skin quality. This method is not only safe and promotes rapid healing but also regenerates and stimulates the growth of new cells to replace old ones, thereby filling pitted scars.

However, this method is contraindicated for patients suffering from platelet disorders, sepsis, Hepatitis B, C, or HIV.

Exosome mesotherapy

Exosome Mesotherapy involves the micro-injection of exosomes into scar areas to enhance wound healing capabilities and collagen deposition, thereby helping to fill pitted scars. Exosomes are extracellular vesicles of microscopic size (40 – 150nm) containing growth factors (EGF), peptides, amino acids, lipids, DNA, RNA, and miRNA. These components serve as signaling molecules between cells, stimulating vigorous fibroblast activity, which promotes collagen production and firms skin tissue. At Doctor Acnes, the exosome treatment for pitted scars utilizes two premium exosome product lines:

• Stem Cell-Exosome Bombit HSC: contains exosomes extracted from mesenchymal stem cells, helping to increase collagen density, repair scar tissue, and fill concave skin areas.

• Exo Booster: an intensive formula combining exosomes from umbilical cord blood, hyaluronic acid, peptides, vitamins, and minerals, supporting the recovery of long-standing scars, lifting scar bases, and improving the skin structure in scarred areas.

PDRN mesotherapy 

PDRN Mesotherapy involves the micro-injection of low molecular weight DNA chains extracted from salmon sperm to repair damaged skin foundations and support the filling of pitted scars.

At Doctor Acnes, the PDRN meso protocol uses Bombit PDRN Ampoule, containing pure sodium DNA capable of stimulating fibroblasts to proliferate collagen, improving skin tissue thickness, and supporting the filling of shallow to medium pitted scars.

This method is suitable for pitted scar cases requiring rapid recovery after invasive treatments such as fractional laser, microneedling, RF microneedling, or for those wishing to improve a damaged skin foundation.

Polynucleotide (PN) mesotherapy – Rejuran S

Rejuran utilizes DOT (DNA Optimizing Technology) to maintain the natural structure and high bio-activity of polynucleotides (PN) extracted from salmon. Consequently, the PN active ingredient in Rejuran is capable of deeply repairing damaged skin tissue, promoting cell regeneration, and effectively supporting the filling of pitted scars.

Unlike standard PDRN products, Rejuran possesses longer nucleotide chains and a higher nucleotide content, thereby strongly enhancing collagen synthesis, improving connective tissue density, and reinforcing a solid skin foundation.

At Doctor Acnes, the Rejuran S injection protocol is indicated for long-standing scars or weak skin requiring foundation restoration. This method not only helps fill scar bases and improve firmness but also restores the overall health and radiance of the skin.

Juvelook biostimulator mesotherapy

Biostimulator mesotherapy for scars at Doctor Acnes uses Juvelook, a formula combining hyaluronic acid (HA) and Poly D, L-Lactic Acid (PDLLA) from Korea. When injected into the scar base, the microspheres dissolve slowly and activate a continuous regeneration mechanism, helping to lift the skin from within and significantly improving pitted scars.

Thanks to its prolonged stimulation capability, the effects can be maintained for up to 12 months. This method is suitable for long-standing scars, deep scar bases, or cases difficult to improve with conventional therapies.

Mesotherapy for acnes treatment and corticosteroid-damaged skin

Depending on the specific skin condition, Dermatologists at Doctor Acnes will prescribe appropriate ingredients, among which peptides are a key component commonly found in all recovery injection protocols. Peptides are short chains of amino acids that help build protein structures such as collagen, elastin, and keratin.

Additionally, ingredients such as niacinamide, hyaluronic acid, amino acids, pantothenic acid, pyridoxine, biotin, vitamins, and zinc are used to help regenerate the skin, restore protective barrier function, and enhance the immune system to strengthen the skin. They also provide antioxidant effects, slow down the aging process, and improve uneven skin tone.

Exosome recovery mesotherapy

Exosome recovery mesotherapy at Doctor Acnes involves the micro-injection of concentrated exosome products combined with peptides, PDRN, amino acids, and growth factors. This aims to enhance the recovery of damaged skin tissue, improve elasticity, and brighten the skin tone. The products used in this treatment include:

• Exo Booster: contains concentrated exosomes, hyaluronic acid, PDRN, peptides, growth factors, amino acids, and vitamins. This formula promotes the recovery of damaged skin tissue, improves elasticity, stimulates collagen production, and brightens and revitalizes the skin.

• Exo Ultra Booster: an upgraded version of Exo Booster, supplemented with potent antioxidants such as glutathione and Vitamin C, alongside skin-restructuring ingredients like hyaluronic acid, PDRN, peptides, and growth factors. This product not only supports deep recovery but also helps reduce wrinkles, improve elasticity, brighten skin tone, and enhance the skin’s defense against aging agents.

• Stem Cell-Exosome Bombit: utilizes MSC-Exosomes extracted from mesenchymal stem cells, combined with glutathione, ceramide, and B-group vitamins, helping to improve elasticity, smooth the skin, and reduce dark spots and pigmentation.

Polynucleotide (PN) skin recovery mesotherapy – Rejuran Healer

This skin recovery mesotherapy protocol uses products containing Polynucleotides (PN) – long DNA chains extracted from salmon, optimized by DOT (DNA Optimizing Technology). This helps stimulate cell regeneration, restore damaged skin foundations, improve elasticity, and promote natural collagen production.

Compared to conventional DNA extract active ingredients, Rejuran Healer possesses longer nucleotide chains and a higher nucleotide content, delivering deep skin tissue recovery and maintaining more sustainable results.

This method is particularly suitable for aging skin, damaged skin, or long-standing pitted scars, helping to reinforce the skin matrix structure, fill hollow areas, increase firmness, and improve the overall brightness, health, and elasticity of the skin.

PDRN recovery mesotherapy

This protocol uses Bombit PDRN Ampoule, extracted from Polydeoxyribonucleotide (PDRN), which are low molecular weight DNA chains derived from salmon.

This treatment helps stimulate fibroblasts to proliferate collagen, recover damaged tissue, improve skin elasticity, and reinforce the natural protective barrier. Simultaneously, PDRN supports inflammation relief and promotes the skin repair process following invasive treatments.

This method is suitable for cases of weak skin following fractional laser, microneedling, or mildly damaged skin requiring restoration of skin thickness and health.

PRP skin recovery and regeneration mesotherapy

The PRP skin recovery and regeneration mesotherapy protocol utilizes autologous platelet-rich plasma to stimulate collagen production, regenerate new skin cells, and improve skin elasticity. This treatment supports skin strengthening, scar filling, and pigmentation reduction, resulting in skin that is bright, smooth, even-toned, and full of vitality.

Mesotherapy for acne treatment

Mesotherapy delivers acne treatment active ingredients directly through the skin surface into acne lesions or the dermis. This bypasses the absorption barrier of the stratum corneum as well as chemical degradation occurring on the skin surface, thereby delivering superior acne treatment efficacy.

Doctor Acnes Dermatology Clinic utilizes products containing salicylic acid, retinyl palmitate, pyruvic acid, zinc, niacinamide, and peptides. These are highly effective active ingredients for treating acne, regulating sebum production, and minimizing pores.

Mesotherapy for skin brightening

Mesotherapy for skin brightening is a micro-injection procedure using products containing skin-brightening agents, antioxidants, and ingredients that support hyperpigmentation reduction. Key active ingredients include tranexamic acid, arbutin, vitamin C, glutathione, and herbal extracts, which help inhibit melanin production, brighten and even out skin tone, and improve dark spots and melasma. The products used in this treatment include:

• Tranacix: contains 10% tranexamic acid, supporting the inhibition of hyperpigmentation, brightening the skin, fading dark spots, and limiting side effects on the skin.

• Infini Premium Meso WhiteningMax: contains tranexamic acid, glutathione, arbutin, kojic acid, and hyaluronic acid, combined with oligopeptide-34 and 13 synthetic amino acids. It supports melanin inhibition, fades melasma and dark spots, while moisturizing and restoring dull skin.

• Dermica Whitelan Step 2: contains arbutin, niacinamide, tranexamic acid, vitamin C, and kojic acid, supporting the fading of dark spots, brightening the skin, and effectively preventing aging.

Mesotherapy for skin glowing

The most commonly used active ingredient in skin rejuvenation mesotherapy is hyaluronic acid. When hyaluronic acid is injected directly into the skin, it stimulates fibroblasts to synthesize collagen and elastin, helping to increase skin elasticity and minimize wrinkles. At Doctor Acnes, Dermatologists combine high concentrations of hyaluronic acid with other nutrients such as amino acids, antioxidants, vitamin B6, zinc gluconate, copper tripeptide, retinyl palmitate, and vitamin C to help the skin become glowing, restored, full of vitality, and more youthful. The products used in this treatment include:

• RRS Hyalift 75: contains 75mg of natural hyaluronic acid and 15 bioactive agents, helping to restore weak skin foundations and proliferate collagen.

• Teosyal Puresense Redensity 1: a formula of hyaluronic acid combined with essential nutrients and lidocaine, supporting deep hydration, skin brightening, and elasticity improvement.

• Exo Booster & Ultra Booster: a duo containing exosomes, peptides, growth factors, and hyaluronic acid, helping to restructure the skin foundation, brighten, and increase radiant smoothness.

• Peptidyal 86HX: contains a high concentration of hyaluronic acid combined with calcium hydroxyapatite (CaHA) and essential amino acids such as proline, glycine, and lysine, helping to proliferate collagen, restructure the skin foundation, improve elasticity, and deliver long-lasting glowing, healthy skin.

Mesotherapy for skin glowing and pores shrinking

Mesotherapy for skin glowing and pores shrinking is a procedure involving the even injection of a small amount of diluted botox (botulinum toxin) combined with hyaluronic acid into the dermis. This helps the facial skin become smooth, tightens pores, and reduces sebum and sweat secretion.

Skinbooster mesotherapy

Skinbooster mesotherapy is a micro-injection procedure into the dermis using a high concentration hyaluronic acid (HA) formula, with or without cross-linking, combined with supporting active ingredients to enhance water retention and restructure the skin foundation. Unlike conventional mesotherapy treatments that only provide temporary hydration, skinboosters help maintain long-term results, improving the elasticity, smoothness, and vitality of the skin from within. This method is particularly suitable for dry skin, mild aging, or loss of elasticity, helping to restore the natural plumpness and firmness of the skin. The effect lasts on average from 6 to 9 months after treatment, superior to conventional HA mesotherapy which typically maintains effectiveness for only 1 to 3 months. At Doctor Acnes, we use premium skinbooster products:

• Belotero Revive: applies exclusive Cohesive Polydensified Matrix (CPM®) Technology, creating a homogeneous HA gel structure that ensures stable distribution within skin tissue and prolongs treatment efficacy. The product contains 20mg/ml of cross-linked hyaluronic acid combined with glycerol, an active ingredient with high water-attracting and retaining capabilities, while also strengthening the skin barrier and reducing transepidermal water loss. Consequently, Belotero Revive helps comprehensively improve moisture, elasticity, and surface brightness, delivering soft, naturally glowing skin.

• Juvéderm Volite: applies exclusive Vycross technology, optimizing the HA molecular structure by combining long and short-chain HA, creating a durable cross-linked network that helps distribute evenly in skin tissue and prolongs residence time. The product improves skin hydration, elasticity, and smoothness.

• Restylane Vital Light: part of the Restylane filler line by Galderma (Sweden), containing mildly cross-linked HA (12mg/ml) using exclusive NASHA technology. Suitable for delicate, dry, sensitive skin and the area around the eyes. Restylane Vital Light helps provide deep hydration, improve pigmentation, fade fine lines, and increase natural elasticity, with results lasting up to 15 months.

• Peptidyal 86HX: utilizes a high concentration HA base combined with calcium hydroxyapatite (CaHA) and a trio of amino acids (proline, glycine, lysine). HA delivers distinct glow and hydration, while CaHA creates a supportive structure similar to a biological scaffold, activating fibroblasts and promoting collagen regeneration over time. Thanks to the durable tissue regeneration process, the skin foundation quality gradually improves in elasticity, and the rejuvenation effect is maintained longer.